I do need to ask if the heavy side is exceeding a tire rating or the axle rating? This would necessitate a more aggressive action if so.
I would look for items I could move to help the balance. Every little thing adds up and remember, just 50 pounds going to the other side equals a 100 pound difference; -50 pounds on one side and +50 pounds on the other, we are now 100 pounds closer to being balanced.
The RV Safety & Education Foundation recommends inflating trailer tires to the sidewall inflation pressure unless we have individual wheel position weights to work with. A one-inch difference in ride height on a trailer is not very much, considering the big picture, but simply adding a band-aid to make the unit level will not cure the load issue. The heavy side will still be the heavy side though it will simply appear to sit level.
Balancing the load and having the correct inflation pressures will have the most positive effect on tire wear, however, all the issues you bring up will contribute to uneven tire wear.